SCHEMBL25510072

SCHEMBL25510072

CCC(Cc1ccc2ccccn12)NC

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 0.37
HPGD P15428 1/20 0.35
HTR1B P28222 4/20 0.33
GPR139 Q6DWJ6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25510173 0.89 SLC6A4 (0.38) SLC6A4HPGDHTR1BGPR139
SCHEMBL25515345 0.81 TAAR1 (0.46) SLC6A4
SCHEMBL25509953 0.81 TAAR1 (0.46) SLC6A4
SCHEMBL25510071 0.78 HTR2A (0.36) SLC6A4
SCHEMBL25175015 0.76
SCHEMBL25510070 0.75 SIGMAR1 (0.49) SLC6A4
SCHEMBL7169853 0.74 ALDH1A1 (0.37) HPGD
SCHEMBL25515982 0.73 SLC6A4 (0.42) SLC6A4HTR1B
SCHEMBL25509951 0.70 SLC6A4 (0.42) SLC6A4HPGDHTR1B
SCHEMBL25510168 0.69 TAAR1 (0.43) SLC6A4HTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023081306-A1 INDOLIZINE COMPOUNDS FOR THE TREATMENT OF MENTAL DISORDERS OR MENTAL ENHANCEMENT TACTOGEN INC (US) 2023-05-11 WO disclosed