Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25509953 | 1.00 | TAAR1 (0.46) | TAAR1SLC18A2SIGMAR1SLC6A4CYP2D6 | |
| SCHEMBL25510168 | 0.88 | TAAR1 (0.43) | TAAR1SLC18A2SIGMAR1SLC6A4CYP2D6 | |
| SCHEMBL25510070 | 0.84 | SIGMAR1 (0.49) | SIGMAR1SLC6A4CYP2D6MAPT | |
| SCHEMBL25510072 | 0.81 | SLC6A4 (0.37) | SLC6A4 | |
| SCHEMBL25515982 | 0.79 | SLC6A4 (0.42) | TAAR1SIGMAR1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL25175015 | 0.78 | — | — | |
| SCHEMBL25510071 | 0.73 | HTR2A (0.36) | SLC6A4ALDH1A1KDM4ECHEK1MAPT | |
| SCHEMBL7169853 | 0.72 | ALDH1A1 (0.37) | ALDH1A1KDM4ECHEK1MAPTLIMK1 | |
| SCHEMBL25510170 | 0.72 | SIGMAR1 (0.46) | SIGMAR1SLC6A4MAPT | |
| SCHEMBL14339186 | 0.71 | KDM4E (0.33) | ALDH1A1KDM4ECHEK1MAPTLIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081306-A1 | INDOLIZINE COMPOUNDS FOR THE TREATMENT OF MENTAL DISORDERS OR MENTAL ENHANCEMENT | TACTOGEN INC (US) | 2023-05-11 | — | — | WO | disclosed |