Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 6/20 | 0.41 |
| ▸ | DRD1 | P21728 | 6/20 | 0.41 |
| ▸ | DRD5 | P21918 | 6/20 | 0.41 |
| ▸ | DRD3 | P35462 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25512684 | 0.84 | L3MBTL1 (0.48) | L3MBTL1DRD2DRD1DRD5DRD3 | |
| SCHEMBL25512674 | 0.83 | L3MBTL1 (0.44) | L3MBTL1DRD2DRD1DRD5DRD3 | |
| SCHEMBL25514167 | 0.82 | L3MBTL1 (0.43) | L3MBTL1DRD2DRD1DRD5DRD3 | |
| SCHEMBL25512782 | 0.82 | DRD2 (0.43) | L3MBTL1DRD2DRD1DRD5DRD3 | |
| SCHEMBL25512694 | 0.81 | L3MBTL1 (0.42) | L3MBTL1DRD2DRD1DRD5DRD3 | |
| SCHEMBL25512663 | 0.81 | L3MBTL1 (0.42) | L3MBTL1DRD2DRD1DRD5DRD3 | |
| SCHEMBL25514123 | 0.81 | L3MBTL1 (0.42) | L3MBTL1DRD2DRD1DRD5DRD3 | |
| SCHEMBL25512792 | 0.80 | L3MBTL1 (0.40) | L3MBTL1DRD2DRD1DRD5DRD3 | |
| SCHEMBL25512678 | 0.80 | TLR9 (0.44) | L3MBTL1DRD2DRD1DRD5DRD3 | |
| SCHEMBL25512680 | 0.79 | HTR6 (0.45) | L3MBTL1DRD2DRD1DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159544-A1 | AZEPINO-INDOLES FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | TERRAN BIOSCIENCES INC (US) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159544-A1 | AZEPINO-INDOLES FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | TPH2, TPH1, SLC18A2 | L3MBTL1 3771/4885DRD2 61/4885DRD1 92/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.