Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 9/20 | 0.47 |
| ▸ | DRD1 | P21728 | 9/20 | 0.47 |
| ▸ | DRD5 | P21918 | 9/20 | 0.47 |
| ▸ | DRD3 | P35462 | 8/20 | 0.47 |
| ▸ | DRD4 | P21917 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25512661 | 0.89 | HTR6 (0.52) | HTR6KDM4ECHRNA7DRD2DRD1 | |
| SCHEMBL25513636 | 0.87 | HTR6 (0.45) | HTR6KDM4ECHRNA7DRD2DRD1 | |
| SCHEMBL25514115 | 0.85 | HTR6 (0.48) | HTR6KDM4ECHRNA7DRD2DRD1 | |
| SCHEMBL25512786 | 0.82 | HTR6 (0.48) | HTR6KDM4ECHRNA7DRD2DRD1 | |
| SCHEMBL25513558 | 0.82 | HTR6 (0.48) | HTR6KDM4ECHRNA7DRD2DRD1 | |
| SCHEMBL25512689 | 0.81 | L3MBTL1 (0.61) | KDM4ECHRNA7DRD2DRD1DRD5 | |
| SCHEMBL25513613 | 0.79 | KDM4E (0.50) | HTR6KDM4ECHRNA7DRD2DRD1 | |
| SCHEMBL25192385 | 0.77 | CYP2D6 (0.64) | HTR6KDM4ECHRNA7DRD2DRD1 | |
| SCHEMBL29564708 | 0.77 | CYP2D6 (0.64) | HTR6KDM4ECHRNA7DRD2DRD1 | |
| SCHEMBL25419634 | 0.77 | KDM4E (0.48) | HTR6KDM4ECHRNA7DRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159544-A1 | AZEPINO-INDOLES FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | TERRAN BIOSCIENCES INC (US) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159544-A1 | AZEPINO-INDOLES FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | TPH2, TPH1, SLC18A2 | HTR6 31/4885KDM4E 780/4885CHRNA7 167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.