SCHEMBL29564708

SCHEMBL29564708

COc1ccc2c3c([nH]c2c1)CCN(C)CC3

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 3/20 0.64
HSD17B10 Q99714 3/20 0.64
CYP1A2 P05177 2/20 0.64
USP2 O75604 1/20 0.64
CYP2C9 P11712 1/20 0.64
ALOX15 P16050 1/20 0.64
DRD2 P14416 4/20 0.62
DRD1 P21728 4/20 0.62
DRD5 P21918 4/20 0.62
DRD3 P35462 4/20 0.62
HTR7 P34969 2/20 0.60
ADRA2A P08913 1/20 0.60
ADRA2B P18089 1/20 0.60
ADRA2C P18825 1/20 0.60
NISCH Q9Y2I1 1/20 0.60
KDM4E B2RXH2 4/20 0.51
MEN1 O00255 2/20 0.51
ALDH1A1 P00352 2/20 0.51
GLA P06280 2/20 0.51
CYP3A4 P08684 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25192385 1.00 CYP2D6 (0.64) CYP2D6HSD17B10CYP1A2USP2CYP2C9
SCHEMBL25192202 0.91 CYP2D6 (0.53) CYP2D6HSD17B10CYP1A2USP2CYP2C9
SCHEMBL25183522 0.91 HTR7 (0.56) CYP2D6HSD17B10CYP1A2USP2CYP2C9
SCHEMBL18034945 0.90 CYP2D6 (0.62) CYP2D6HSD17B10CYP1A2USP2CYP2C9
Fumaric Acid SCHEMBL30424752 0.89 HTR7 (0.53) CYP2D6HSD17B10CYP1A2USP2CYP2C9
Fumaric Acid SCHEMBL25201865 0.89 HTR7 (0.53) CYP2D6HSD17B10CYP1A2USP2CYP2C9
SCHEMBL25774052 0.85 HTR7 (0.54) CYP2D6HSD17B10CYP1A2USP2CYP2C9
SCHEMBL25187618 0.85 DRD2 (0.47) CYP2D6HSD17B10CYP1A2USP2CYP2C9
SCHEMBL25190777 0.84 HTR7 (0.56) CYP2D6HSD17B10CYP1A2USP2CYP2C9
SCHEMBL25512795 0.84 HTR7 (0.53) CYP2D6HSD17B10CYP1A2USP2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250360150-A1 METHODS OF USING NEUROPLASTIC AGENTS AND TERRAFORMING MARS BRANNOCK METCALF MOLLY CAROLINE (US) 2025-11-27 US claimed
EP-4547250-A1 METHODS AND COMPOSITIONS RELATING TO CONTROLLING PSYCHEDELIC EFFECTS WITH SEROTONIN RECEPTOR MODULATORS Terran Biosciences Inc. (US) 2025-05-07 EP claimed
US-20240197681-A1 METHODS AND COMPOSITIONS RELATING TO PSYCHEDELICS AND SEROTONIN RECEPTOR MODULATORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-06-20 US claimed
US-11905295-B2 Solid forms of tabernanthalog monofumarate salt for treating neurological disorders and/or psychiatric disorders TERRAN BIOSCIENCES INC. (US) 2024-02-20 US claimed
EP-4313030-A1 METHODS AND COMPOSITIONS RELATING TO PSYCHEDELICS AND SEROTONIN RECEPTOR MODULATORS Terran Biosciences, Inc. (US) 2024-02-07 EP claimed
WO-2024006984-A1 METHODS AND COMPOSITIONS RELATING TO CONTROLLING PSYCHEDELIC EFFECTS WITH SEROTONIN RECEPTOR MODULATORS TERRAN BIOSCIENCES INC. (US) 2024-01-04 WO claimed
US-20230279017-A1 SALT AND SOLID FORMS OF TABERNANTHALOG TERRAN BIOSCIENCES INC. 2023-09-07 US claimed
US-20230257385-A1 SALT AND SOLID FORMS OF TABERNANTHALOG TERRAN BIOSCIENCES INC (US) 2023-08-17 US claimed
WO-2023092045-A1 SALT AND SOLID FORMS OF TABERNANTHALOG TERRAN BIOSCIENCES, INC. (US) 2023-05-25 WO claimed
WO-2022212854-A1 METHODS AND COMPOSITIONS RELATING TO PSYCHEDELICS AND SEROTONIN RECEPTOR MODULATORS TERRAN BIOSCIENCES INC. (US) 2022-10-06 WO claimed
US-20260138985-A1 Azepino-Indoles for the Treatment of Neurological and Psychiatric Disorders TERRAN BIOSCIENCES INC (US) 2026-05-21 US disclosed
CN-122028945-A Apparatus, systems, and methods for aerosolized drug administration GH研究爱尔兰有限公司 2026-05-12 CN disclosed
EP-3861977-B1 (METH)ACRYLATE, MONOMER COMPOSITION, MOLDED BODY, COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL MITSUI CHEMICALS INC (JP) 2026-05-06 EP disclosed
EP-4728531-A1 BIOADAPTIVE THERAPEUTIC ENVIRONMENTS Therapod LLC (US) 2026-04-22 EP disclosed
US-12577232-B2 N-heterocycle substituted tryptamine derivatives and methods of using Enveric Biosciences Canada Inc. (CA) 2026-03-17 US disclosed
WO-2022232933-A1 PERSONALIZED MICRODOSING KITS AND PROTOCOLS BASED ON BIOMETRIC AND MOVEMENT DATA CORRELATED WITH NATURAL PRODUCT QUALITIES RED LIGHT HOLLAND CORP. (CA) 2022-11-10 WO disclosed
WO-2022212854-A1 METHODS AND COMPOSITIONS RELATING TO PSYCHEDELICS AND SEROTONIN RECEPTOR MODULATORS TERRAN BIOSCIENCES INC. (US) 2022-10-06 WO disclosed
US-11414423-B1 Substituted 1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles for treating brain disorders THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-08-16 US disclosed
CN-110824065-B Method for detecting embedded lycopene 南京中科药业有限公司 2022-07-26 CN disclosed
WO-2022081631-A1 GPCR SCREENING METHOD TO IDENTIFY NON-HALLUCINOGENIC COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-04-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11414423-B1 Substituted 1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles for treating brain disorders HTR2C, HTR4, HTR2B CYP2D6 335/4885HSD17B10 866/4885CYP1A2 446/4885
US-20230257385-A1 SALT AND SOLID FORMS OF TABERNANTHALOG SLC6A2, SLC6A4, SLC6A3 CYP2D6 114/4885HSD17B10 325/4885CYP1A2 344/4885
US-20260138985-A1 Azepino-Indoles for the Treatment of Neurological and Psychiatric Disorders TPH2, TPH1, HTR1D CYP2D6 428/4885HSD17B10 944/4885CYP1A2 115/4885
US-20240197681-A1 METHODS AND COMPOSITIONS RELATING TO PSYCHEDELICS AND SEROTONIN RECEPTOR MODULATORS HTR1A, HTR2A, HTR3A CYP2D6 1202/4885HSD17B10 3662/4885CYP1A2 1113/4885
US-20230279017-A1 SALT AND SOLID FORMS OF TABERNANTHALOG SLC6A2, SLC6A4, SLC6A3 CYP2D6 114/4885HSD17B10 325/4885CYP1A2 344/4885
US-11905295-B2 Solid forms of tabernanthalog monofumarate salt for treating neurological disorders and/or psychiatric disorders FAH, SLC6A3, SLC6A2 CYP2D6 130/4885HSD17B10 271/4885CYP1A2 401/4885
US-12577232-B2 N-heterocycle substituted tryptamine derivatives and methods of using HTR2C, TPH2, HTR4 CYP2D6 98/4885HSD17B10 2613/4885CYP1A2 112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.