Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.42 |
| ▸ | GSK3B | P49841 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.32 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6248007 | 0.82 | L3MBTL1 (0.40) | L3MBTL1HTTATMALDH1A1GAA | |
| SCHEMBL31183044 | 0.82 | PTGS2 (0.35) | L3MBTL1HTTATMALDH1A1TDP1 | |
| SCHEMBL25515352 | 0.78 | MAPT (0.36) | L3MBTL1HTTATMALDH1A1TDP1 | |
| SCHEMBL6276005 | 0.77 | HSD17B3 (0.40) | L3MBTL1HTTATMALDH1A1MAPT | |
| SCHEMBL9102928 | 0.76 | BAZ2B (0.39) | L3MBTL1HTTATMALDH1A1TDP1 | |
| SCHEMBL6535007 | 0.75 | ALDH1A1 (0.45) | L3MBTL1ALDH1A1TDP1GAAMAPT | |
| SCHEMBL28070421 | 0.74 | BAZ2B (0.38) | L3MBTL1HTTATMALDH1A1TDP1 | |
| SCHEMBL1646369 | 0.73 | L3MBTL1 (0.35) | L3MBTL1HTTATMALDH1A1MAPT | |
| SCHEMBL29206234 | 0.73 | ALDH1A1 (0.41) | L3MBTL1HTTATMALDH1A1TDP1 | |
| SCHEMBL8122403 | 0.72 | HTT (0.45) | L3MBTL1HTTATMALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081306-A1 | INDOLIZINE COMPOUNDS FOR THE TREATMENT OF MENTAL DISORDERS OR MENTAL ENHANCEMENT | TACTOGEN INC (US) | 2023-05-11 | — | — | WO | disclosed |