Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 3/20 | 0.33 |
| ▸ | BAZ2A | Q9UIF9 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31183049 | 0.89 | MAPT (0.34) | MAPTKDM4ERAB9APOLBALDH1A1 | |
| SCHEMBL6248007 | 0.81 | L3MBTL1 (0.40) | MAPTKDM4ERAB9ASMN1; SMN2POLB | |
| SCHEMBL31183044 | 0.78 | PTGS2 (0.35) | MAPTKDM4ERAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL25515348 | 0.78 | PTPN1 (0.42) | MAPTKDM4ERAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL30147703 | 0.78 | KDM4E (0.41) | MAPTKDM4ERAB9ASMN1; SMN2POLB | |
| SCHEMBL6276005 | 0.76 | HSD17B3 (0.40) | MAPTL3MBTL1HTTATMALDH1A1 | |
| SCHEMBL6535007 | 0.75 | ALDH1A1 (0.45) | MAPTKDM4ERAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL25515640 | 0.75 | MAPT (0.48) | MAPTKDM4ERAB9ASMN1; SMN2POLB | |
| SCHEMBL25510901 | 0.74 | KDM4E (0.35) | MAPTKDM4ERAB9ASMN1; SMN2POLB | |
| SCHEMBL25515107 | 0.73 | THRB (0.37) | MAPTKDM4ERAB9ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081306-A1 | INDOLIZINE COMPOUNDS FOR THE TREATMENT OF MENTAL DISORDERS OR MENTAL ENHANCEMENT | TACTOGEN INC (US) | 2023-05-11 | — | — | WO | disclosed |