Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 8/20 | 0.57 |
| ▸ | CA1 | P00915 | 8/20 | 0.57 |
| ▸ | CA2 | P00918 | 8/20 | 0.57 |
| ▸ | CA6 | P23280 | 8/20 | 0.57 |
| ▸ | CA7 | P43166 | 8/20 | 0.57 |
| ▸ | CA13 | Q8N1Q1 | 8/20 | 0.57 |
| ▸ | CA9 | Q16790 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25516479 | 0.79 | CA12 (0.59) | CA12CA1CA2CA6CA7 | |
| SCHEMBL27358326 | 0.75 | AKR1C3 (0.45) | HPGDMEN1KMT2ARAB9A | |
| SCHEMBL22380991 | 0.73 | CA12 (1.00) | CA12CA1CA2CA6CA7 | |
| SCHEMBL18805093 | 0.72 | ALPG (0.65) | CA12CA1CA2CA6CA7 | |
| SCHEMBL15819579 | 0.70 | AKR1C3 (0.57) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL26741217 | 0.69 | MEN1 (0.54) | MEN1KMT2A | |
| SCHEMBL28617692 | 0.69 | ALDH1A1 (0.43) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6201829 | 0.68 | CA12 (0.64) | CA12CA1CA2CA6CA7 | |
| SCHEMBL25516473 | 0.68 | CDYL2 (0.63) | CA12CA1CA2CA6CA7 | |
| SCHEMBL27435976 | 0.66 | HDAC8 (0.56) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230149403-A1 | CARBONIC ANHYDRASE ENZYMES FOR REGULATING MAST CELL HEMATOPOIESIS AND TYPE 2 INFLAMMATION | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230149403-A1 | CARBONIC ANHYDRASE ENZYMES FOR REGULATING MAST CELL HEMATOPOIESIS AND TYPE 2 INFLAMMATION | CA2, CMA1, CPA3 | CA12 8/4885CA1 10/4885CA2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.