SCHEMBL25519087

SCHEMBL25519087

Cc1cc(C)c(C)c(-c2c3sc4ccccc4c3cc[n+]2C)c1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
MAPT P10636 4/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
POLB P06746 2/20 0.36
HCRTR1 O43613 1/20 0.36
LMNA P02545 1/20 0.36
RAB9A P51151 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ALOX5 P09917 1/20 0.34
ATM Q13315 1/20 0.33
GPR3 P46089 1/20 0.33
PARP14 Q460N5 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2A6 P11509 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
GAA P10253 1/20 0.31
NPC1 O15118 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25823205 0.83
SCHEMBL25823204 0.83
SCHEMBL25445485 0.82 PARP14 (0.38) ALDH1A1MAPTL3MBTL1POLBHCRTR1
SCHEMBL25823199 0.82 ALDH1A1 (0.33) ALDH1A1MAPTL3MBTL1LMNAGAA
SCHEMBL25823206 0.81 LIMK1 (0.36) POLBLMNARAB9AATMKMT2A
SCHEMBL25776747 0.80 MAPT (0.35) ALDH1A1MAPTL3MBTL1POLBHCRTR1
SCHEMBL25519091 0.79 HRH4 (0.39) ALDH1A1MAPTL3MBTL1POLBHCRTR1
SCHEMBL25445486 0.78 MAPT (0.37) ALDH1A1MAPTL3MBTL1POLBHCRTR1
SCHEMBL25518415 0.75 CYP2A6 (0.43) ALDH1A1MAPTLMNAKDM4ECYP1A2
SCHEMBL25776417 0.74 CYP1A2 (0.39) ALDH1A1MAPTL3MBTL1RAB9AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309394-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed
US-20230250118-A1 ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-08-10 US disclosed
US-20230144101-A1 LIGHT-EMITTING MATERIAL WITH A POLYCYCLIC LIGAND Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-05-11 US disclosed
EP-4174078-A1 ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-05-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250118-A1 ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF CRY1, LEF1, PIEZO1 ALDH1A1 500/4885MAPT 1355/4885L3MBTL1 496/4885
US-20230144101-A1 LIGHT-EMITTING MATERIAL WITH A POLYCYCLIC LIGAND TRPC4, CRY1, TRPC1 ALDH1A1 2910/4885MAPT 1111/4885L3MBTL1 1187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.