Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25523958 | 0.81 | NR1H2 (0.46) | NR1H2NR1H3SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL25521799 | 0.69 | TOP2A (0.40) | NR1H2NR1H3KDM4EPTGDR2 | |
| SCHEMBL25521547 | 0.68 | NR1H2 (0.46) | NR1H2NR1H3SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL25523956 | 0.67 | MAPKAPK2 (0.44) | — | |
| SCHEMBL25521916 | 0.62 | ERN1 (0.46) | — | |
| SCHEMBL25522060 | 0.61 | HSP90AA1 (0.34) | — | |
| SCHEMBL4016535 | 0.60 | PIK3CD (0.61) | NR1H2NR1H3SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL25524007 | 0.60 | PDGFRB (0.40) | SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL27809134 | 0.59 | NR4A2 (0.51) | NR1H2NR1H3SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL27809136 | 0.59 | NR4A2 (0.51) | NR1H2NR1H3SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |