Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 9/20 | 0.40 |
| ▸ | BRAF | P15056 | 9/20 | 0.40 |
| ▸ | TNF | P01375 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25523476 | 0.84 | MAPKAPK2 (0.46) | MAPKAPK2RIPK2RETKDRMAPK14 | |
| SCHEMBL25523900 | 0.82 | RAF1 (0.39) | MAPKAPK2RAF1BRAFTNF | |
| SCHEMBL25524046 | 0.80 | TGFBR1 (0.44) | MAPKAPK2TNF | |
| SCHEMBL25522057 | 0.79 | TGFBR1 (0.40) | KDR | |
| SCHEMBL25524005 | 0.76 | TLR8 (0.41) | RIPK2RET | |
| SCHEMBL25522059 | 0.75 | MAP4K4 (0.54) | — | |
| SCHEMBL25524007 | 0.73 | PDGFRB (0.40) | — | |
| SCHEMBL25521800 | 0.72 | AAK1 (0.47) | — | |
| SCHEMBL25524010 | 0.69 | CYP1A2 (0.41) | — | |
| SCHEMBL25521916 | 0.68 | ERN1 (0.46) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |