Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25520064 | 0.82 | TLR8 (0.44) | TLR8RETRIPK1RIPK3RIPK2 | |
| SCHEMBL25522057 | 0.82 | TGFBR1 (0.40) | TLR8EGFRTGFBR1 | |
| SCHEMBL25523900 | 0.78 | RAF1 (0.39) | PDGFRBPDGFRA | |
| SCHEMBL25522336 | 0.77 | TLR8 (0.40) | TLR8RETRIPK1RIPK3RIPK2 | |
| SCHEMBL25523956 | 0.76 | MAPKAPK2 (0.44) | RETRIPK2 | |
| SCHEMBL25524046 | 0.75 | TGFBR1 (0.44) | EGFRTGFBR1 | |
| SCHEMBL25522060 | 0.73 | HSP90AA1 (0.34) | TLR8CCR1CCR5CCR8 | |
| SCHEMBL25524010 | 0.72 | CYP1A2 (0.41) | EGFRPDGFRBPDGFRA | |
| SCHEMBL25524007 | 0.71 | PDGFRB (0.40) | EGFRPDGFRBPDGFRACA1CA2 | |
| SCHEMBL25519630 | 0.69 | AURKA (0.49) | TLR8RETTGFBR1CCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |