Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 8/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30726157 | 0.92 | INPPL1 (0.35) | SYKAAK1CSF1RTLR8CYP3A4 | |
| SCHEMBL27033254 | 0.92 | INPPL1 (0.35) | SYKAAK1CSF1RTLR8CYP3A4 | |
| SCHEMBL27033369 | 0.82 | SYK (0.37) | SYKAAK1CSF1RCYP3A4FLT3 | |
| SCHEMBL25522336 | 0.78 | TLR8 (0.40) | AAK1CSF1RTLR8 | |
| SCHEMBL25520064 | 0.72 | TLR8 (0.44) | TLR8 | |
| SCHEMBL25522342 | 0.66 | NR4A2 (0.40) | SYKAAK1TLR8CYP3A4 | |
| SCHEMBL25522353 | 0.63 | TLR8 (0.38) | TLR8 | |
| SCHEMBL25524005 | 0.62 | TLR8 (0.41) | CSF1RTLR8 | |
| SCHEMBL31538918 | 0.60 | JAK2 (0.33) | AURKB | |
| SCHEMBL25519630 | 0.60 | AURKA (0.49) | CSF1RTLR8FLT3AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558478-A1 | ARYL HYDROCARBON RECEPTOR AGONIST PRODRUGS AND METHODS OF USE THEREOF | Allianthera (Suzhou) Biopharmaceutical Co., Ltd. (CN) | 2025-05-28 | — | — | EP | disclosed |
| WO-2024020170-A1 | ARYL HYDROCARBON RECEPTOR AGONIST PRODRUGS AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2024-01-25 | — | — | WO | disclosed |