Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.33 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25524012 | 0.87 | CYP11B1 (0.38) | EGLN1PDGFRBPDGFRAEGFRRIPK1 | |
| SCHEMBL25523416 | 0.81 | PDGFRB (0.43) | PDGFRBPDGFRAEGFRMAP4K4MET | |
| SCHEMBL25521682 | 0.78 | PDGFRB (0.51) | PDGFRBPDGFRAMAP4K4METCLK4 | |
| SCHEMBL31538928 | 0.78 | PDGFRB (0.51) | PDGFRBPDGFRAMAP4K4METCLK4 | |
| SCHEMBL25523539 | 0.76 | CYP1A2 (0.42) | PDGFRBPDGFRAEGFRMAP4K4CDK8 | |
| SCHEMBL16289110 | 0.70 | CYP1A2 (0.52) | CYP11B1CYP11B2HPGDS | |
| SCHEMBL17460674 | 0.69 | HPGDS (0.48) | EGFRHPGDSMETLRRK2 | |
| SCHEMBL25523536 | 0.69 | PDGFRB (0.39) | PDGFRBPDGFRAEGFRMAP4K4CLK4 | |
| SCHEMBL25523902 | 0.68 | TNIK (0.45) | PDGFRBPDGFRAEGFRMAP4K4MET | |
| SCHEMBL27971152 | 0.68 | CTSS (0.43) | EGFRCYP11B1CYP11B2HPGDSCYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |