Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | AGXT | P21549 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23709488 | 0.86 | ADRA2C (0.54) | ALDH1A1KDM4EGFERL3MBTL1AGXT | |
| SCHEMBL4547919 | 0.83 | NOTUM (0.52) | PRMT6ALDH1A1KDM4EL3MBTL1AGXT | |
| SCHEMBL27408091 | 0.82 | CYP3A4 (0.38) | HDAC4HDAC2HDAC8ALDH1A1LMNA | |
| SCHEMBL3534359 | 0.81 | NOTUM (0.54) | PRMT6ALDH1A1KDM4EGFERL3MBTL1 | |
| SCHEMBL24136303 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EGFERL3MBTL1LMNA | |
| SCHEMBL9839870 | 0.79 | PRMT6 (0.44) | PRMT6ALDH1A1KDM4EGFERL3MBTL1 | |
| SCHEMBL5791930 | 0.78 | PRMT6 (0.47) | PRMT6ALDH1A1KDM4EGFERL3MBTL1 | |
| SCHEMBL24781211 | 0.78 | HDAC4 (0.39) | HDAC4HDAC2HDAC8ALDH1A1KDM4E | |
| SCHEMBL19710909 | 0.78 | RORC (0.43) | HDAC4HDAC2HDAC8ALDH1A1KDM4E | |
| SCHEMBL14703927 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KDM4EGFERL3MBTL1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150946-A1 | HETEROCYCLE CONTAINING STAT INHIBITORS AND COMPOSITIONS | OXFORD FINANCE LLC | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150946-A1 | HETEROCYCLE CONTAINING STAT INHIBITORS AND COMPOSITIONS | STAT5A, STAT5B, STAT3 | PRMT6 1211/4885HDAC4 212/4885HDAC2 279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.