Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 3/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25186768 | 0.71 | TRPV1 (0.42) | RXFP1BRD9MAPK1IDO1METAP1 | |
| SCHEMBL25186778 | 0.69 | LCK (0.39) | RXFP1BRD9IDO1METAP1BRD4 | |
| SCHEMBL25189635 | 0.69 | AAK1 (0.37) | RXFP1BRD9IDO1METAP1BRD4 | |
| SCHEMBL25186762 | 0.68 | RAB9A (0.48) | MAPK1MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL30419303 | 0.68 | RAB9A (0.48) | MAPK1MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL30297391 | 0.67 | RORC (0.40) | — | |
| SCHEMBL2880191 | 0.65 | LMNA (0.54) | RXFP1BRD9METAP1BRD4MEN1 | |
| SCHEMBL2737224 | 0.65 | NLRP3 (0.56) | RXFP1IDO1KMT2A | |
| SCHEMBL2940952 | 0.63 | GAA (0.51) | RXFP1BRD9MAPK1METAP1MEN1 | |
| SCHEMBL12139319 | 0.62 | LMNA (0.46) | RXFP1BRD9IDO1METAP1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |