SCHEMBL25524967

SCHEMBL25524967

Cc1ccc(C[C@H](NC(=O)[C@@H]2CCCN2C(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]2C[C@@H](O)CN2)C(=O)O)cc1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ NMUR2 Q9GZQ4 7/20 0.46
▸ NMUR1 Q9HB89 6/20 0.46
▸ NTSR1 P30989 2/20 0.43
▸ RAMP3 O60896 1/20 0.43
▸ CALCR P30988 1/20 0.43
▸ F2 P00734 4/20 0.42
▸ REN P00797 1/20 0.42
▸ OPRM1 P35372 1/20 0.41
▸ OPRD1 P41143 1/20 0.41
▸ MAPK8 P45983 1/20 0.41
▸ MAPK9 P45984 1/20 0.41
▸ MAPK10 P53779 1/20 0.41
▸ PSMB9 P28065 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22018382 0.95 NMUR2 (0.49) NMUR2NMUR1NTSR1RAMP3CALCR
SCHEMBL22380738 0.94 NMUR2 (0.47) NMUR2NMUR1NTSR1RAMP3CALCR
SCHEMBL22018383 0.92 NAA50 (0.44) NMUR2NMUR1NTSR1RAMP3CALCR
SCHEMBL22018529 0.92 NAA50 (0.44) NMUR2NMUR1RAMP3CALCR
SCHEMBL22018503 0.90 NTSR1 (0.51) NMUR2NMUR1NTSR1RAMP3CALCR
SCHEMBL22018500 0.90 APLNR (0.49) NMUR2NMUR1NTSR1F2REN
SCHEMBL22018493 0.90 RAMP3 (0.43) RAMP3CALCRF2
SCHEMBL29308396 0.90 RAMP3 (0.43) RAMP3CALCRF2
SCHEMBL22018310 0.89 NAA50 (0.42) NMUR2NMUR1RAMP3CALCRREN
SCHEMBL22380817 0.89 NAA50 (0.42) NMUR2NMUR1RAMP3CALCRREN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS YUYU PHARMA, INC. (KR) 2023-05-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS VIP, TSLP, IAPP NMUR2 1237/4885NMUR1 1052/4885NTSR1 561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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