SCHEMBL22018500

SCHEMBL22018500

CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1C[C@@H](O)CN1)C(=O)N[C@@H](C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ APLNR P35414 3/20 0.49
▸ REN P00797 1/20 0.49
▸ OPRD1 P41143 5/20 0.49
▸ NMUR2 Q9GZQ4 3/20 0.48
▸ NMUR1 Q9HB89 3/20 0.48
▸ F2 P00734 1/20 0.47
▸ OPRM1 P35372 7/20 0.47
▸ OPRK1 P41145 7/20 0.47
▸ NTSR1 P30989 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22018606 0.97 OPRD1 (0.48) APLNRRENOPRD1NMUR2F2
SCHEMBL22018503 0.96 NTSR1 (0.51) OPRD1NMUR2NMUR1OPRM1OPRK1
SCHEMBL29308367 0.95 BCL2L1 (0.48) OPRD1F2OPRM1OPRK1
SCHEMBL22018502 0.94 APLNR (0.48) APLNROPRD1NMUR2NMUR1OPRM1
SCHEMBL22018314 0.94 APLNR (0.48) APLNROPRD1NMUR2NMUR1OPRM1
SCHEMBL22018810 0.94 APLNR (0.48) APLNROPRD1NMUR2NMUR1OPRM1
SCHEMBL22018809 0.94 APLNR (0.48) APLNROPRD1NMUR2NMUR1OPRM1
SCHEMBL22018340 0.94 APLNR (0.48) APLNROPRD1NMUR2NMUR1OPRM1
SCHEMBL22018363 0.94 APLNR (0.48) APLNROPRD1NMUR2NMUR1OPRM1
SCHEMBL22018380 0.94 APLNR (0.48) APLNROPRD1NMUR2NMUR1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037415-B2 Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient YUYU PHARMA, INC. (KR) 2024-07-16 — — US disclosed
US-20230312648-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2023-10-05 — — US disclosed
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS YUYU PHARMA, INC. (KR) 2023-05-11 — — US disclosed
WO-2021191689-A2 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS YUYU PHARMA, INC. (KR) 2021-09-30 — — WO disclosed
US-20210024577-A1 NOVEL PEPTIDE AND PHARMACEUTICAL COMPOSITION FOR TREATING AN EYE DISEASE COMPRISING THE SAME AS AN ACTIVE PHARMACEUTICAL INGREDIENT YUYU PHARMA, INC. (KR) 2021-01-28 — — US disclosed
US-20200270306-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2020-08-27 — — US disclosed
WO-2020099925-A2 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2020-05-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312648-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES VIP, IAPP, SCTR APLNR 85/4885REN 907/4885OPRD1 3721/4885
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS VIP, TSLP, IAPP APLNR 90/4885REN 619/4885OPRD1 2266/4885
US-20210024577-A1 NOVEL PEPTIDE AND PHARMACEUTICAL COMPOSITION FOR TREATING AN EYE DISEASE COMPRISING THE SAME AS AN ACTIVE PHARMACEUTICAL INGREDIENT VIP, NGLY1, PROKR1 APLNR 279/4885REN 1235/4885OPRD1 3847/4885
US-12037415-B2 Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient VIP, IAPP, NGLY1 APLNR 334/4885REN 1013/4885OPRD1 3752/4885
US-20200270306-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES VIP, IAPP, SCTR APLNR 85/4885REN 907/4885OPRD1 3721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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