Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | CDK1 | P06493 | 6/20 | 0.46 |
| ▸ | ULK1 | O75385 | 2/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.44 |
| ▸ | GPR39 | O43194 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25204693 | 0.77 | MAPT (0.46) | EGFRCDK1RAB9AKDRMAPT | |
| SCHEMBL25239800 | 0.75 | SDHB (0.46) | EGFRCDK1RAB9AKDRCDK2 | |
| SCHEMBL30397985 | 0.75 | SDHB (0.46) | EGFRCDK1RAB9AKDRCDK2 | |
| SCHEMBL31666577 | 0.73 | CCNK (0.60) | CDK2 | |
| SCHEMBL31666668 | 0.73 | CCNK (0.60) | CDK2 | |
| SCHEMBL25523794 | 0.70 | KDR (0.47) | CDK1ULK1PTK2KDRCDK2 | |
| SCHEMBL16462604 | 0.70 | NUDT1 (0.44) | GPR39RAB9AMAPT | |
| SCHEMBL15221838 | 0.70 | LRRK2 (0.60) | ULK1 | |
| SCHEMBL25529316 | 0.70 | LRRK2 (0.47) | ULK1 | |
| SCHEMBL17547452 | 0.69 | ULK1 (0.79) | EGFRCDK1ULK1PTK2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |