SCHEMBL25527912

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25737050	0.89	CA12 (0.40)	SERPINE1CA12CA1CA2CA7
	SCHEMBL25527941	0.86	SERPINE1 (0.36)	SERPINE1GAA
	SCHEMBL25527923	0.85	KMT2A (0.41)	SERPINE1CA12CA1CA2CA9
	SCHEMBL25737056	0.84	SERPINE1 (0.33)	SERPINE1TDP1L3MBTL1GAA
	SCHEMBL25527965	0.83	KMT2A (0.43)	MAPTKDM4EGAAKMT2A
	SCHEMBL25737065	0.82	ALDH1A1 (0.44)	SERPINE1CA1CA2TDP1POLB
	SCHEMBL25737057	0.82	CYP4F2 (0.47)	POLBKDM4EKMT2A
	SCHEMBL25737060	0.82	MAPK1 (0.34)	SERPINE1CA1CA2TYRGAA
	SCHEMBL25527981	0.81	PTGS2 (0.38)	SERPINE1MAPTKDM4EGAAKMT2A
	SCHEMBL25476179	0.80	SERPINE1 (0.51)	SERPINE1CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.