SCHEMBL25527923

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25737057	0.89	CYP4F2 (0.47)	KMT2ACYP4F2CYP4A11ALDH1A1MEN1
	SCHEMBL25527941	0.85	SERPINE1 (0.36)	ALDH1A1SERPINE1
	SCHEMBL25527912	0.85	SERPINE1 (0.49)	KMT2ASERPINE1MAPTTDP1CA12
	SCHEMBL25737056	0.83	SERPINE1 (0.33)	CYP4F2CYP4A11ALDH1A1SERPINE1NPC1
	SCHEMBL18775878	0.83	KMT2A (0.53)	KMT2ACHRM2CHRM3MAOAHTR2C
	SCHEMBL25737050	0.82	CA12 (0.40)	ALDH1A1SERPINE1TDP1HPGDCA12
	SCHEMBL25527965	0.82	KMT2A (0.43)	KMT2AMEN1NPC1MAPTRAB9A
	SCHEMBL25737065	0.81	ALDH1A1 (0.44)	KMT2ACYP4F2CYP4A11ALDH1A1SERPINE1
	SCHEMBL25737060	0.81	MAPK1 (0.34)	CYP4F2CYP4A11ALDH1A1SERPINE1HPGD
	SCHEMBL25476191	0.81	NPC1 (0.46)	KMT2ACHRM2CHRM3MAOAHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.