SCHEMBL1022153

SCHEMBL1022153

COC(=O)C(C)(C)C(C)=O

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.56
ALDH1A1 P00352 3/20 0.42
ELANE P08246 1/20 0.36
KCNN4 O15554 1/20 0.34
GAA P10253 2/20 0.33
MGAM O43451 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
MAPT P10636 1/20 0.31
SRC P12931 1/20 0.31
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18778754 0.97 DGAT1 (0.54) DGAT1ALDH1A1ELANEKCNN4GAA
SCHEMBL7196086 0.87 DGAT1 (0.50) DGAT1ALDH1A1ELANEKCNN4GAA
SCHEMBL808799 0.84 DGAT1 (0.74) DGAT1ALDH1A1ELANEKCNN4GAA
SCHEMBL23091415 0.81 DGAT1 (0.70) DGAT1ALDH1A1ELANEKCNN4GAA
Iodide SCHEMBL10533676 0.81 DGAT1 (0.70) DGAT1ALDH1A1ELANEKCNN4GAA
Ammonia Solution, Strong SCHEMBL7639328 0.81 DGAT1 (0.70) DGAT1ALDH1A1ELANEKCNN4GAA
SCHEMBL29084303 0.79 ALDH1A1 (0.37) DGAT1ALDH1A1GAATSHR
SCHEMBL248324 0.79 DGAT1 (0.35) DGAT1ALDH1A1GAATSHR
SCHEMBL5859056 0.79 DGAT1 (0.59) DGAT1ALDH1A1ELANEKCNN4SRC
SCHEMBL1010735 0.77 DGAT1 (0.56) DGAT1ALDH1A1ELANEKCNN4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 393 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114478627-A Allylation monophosphine ligand and preparation method thereof 湖北大学 2022-05-13 CN claimed
US-H2219-H1 Method for coating small particles THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2008-07-01 US claimed
US-12545662-B2 MK2 inhibitors and uses thereof XINTHERA, INC. (US) 2026-02-10 US disclosed
EP-3717459-B1 COMPOUNDS STEP PHARMA S A S (FR) 2026-01-21 EP disclosed
US-12503466-B2 Aminothiazole compounds as inhibitors of CTPS1 STEP PHARMA S.A.S. (FR) 2025-12-23 US disclosed
US-RE50453-E1 Indole derivatives as CFTR modulators VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-06-10 US disclosed
US-20250163063-A1 INHIBITORS OF CDK4/6 KINASE KHORA SPV 1, LLC 2025-05-22 US disclosed
WO-2025024707-A1 INHIBITORS OF CDK2/4/6 KINASE KINNATE BIOPHARMA INC. (US) 2025-01-30 WO disclosed
EP-4469062-A1 INHIBITORS OF CDK4/6 KINASE Kinnate Biopharma Inc. (US) 2024-12-04 EP disclosed
CN-119013030-A Inhibitors of CDK4/6 kinase 金耐特生物制药公司 2024-11-22 CN disclosed
US-11987574-B2 MK2 inhibitors and uses thereof XINTHERA, INC. (US) 2024-05-21 US disclosed
WO-1992008701-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed
WO-1992008700-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed
WO-1992008698-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed
US-5110869-A Block polymerization, endcapping, coupling, chain extension E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-05-05 US disclosed
US-4983679-A ENDCAPPING, COUPLING, CHAIN EXTENSION OF POLYMERS E. I. DUPONT DE NEMOURS AND COMPANY (US) 1991-01-08 US disclosed
EP-0272285-A4 ACYLATION AND SULFONATION OF SILYLKETENE ACETALS. DU PONT (US) 1990-04-10 EP disclosed
EP-0272285-A1 ACYLATION AND SULFONATION OF SILYLKETENE ACETALS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-06-29 EP disclosed
WO-1987007265-A1 ACYLATION AND SULFONATION OF SILYLKETENE ACETALS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-12-03 WO disclosed
US-4626543-A PARTICULARY MOTHS SHELL OIL COMPANY (US) 1986-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11987574-B2 MK2 inhibitors and uses thereof MKNK2, ENPP2, MAPKAPK2 DGAT1 2022/4885ALDH1A1 4145/4885ELANE 1770/4885
US-12503466-B2 Aminothiazole compounds as inhibitors of CTPS1 CTPS1, CTPS2, TBXAS1 DGAT1 536/4885ALDH1A1 3425/4885ELANE 2883/4885
US-20250163063-A1 INHIBITORS OF CDK4/6 KINASE CDK4, CDK6, CDK2 DGAT1 2885/4885ALDH1A1 2737/4885ELANE 4074/4885
US-12545662-B2 MK2 inhibitors and uses thereof NR3C2, NR2C2, AGTR2 DGAT1 985/4885ALDH1A1 3116/4885ELANE 1901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.