Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25528468 | 0.91 | CACNA1H (0.36) | CACNA1HLMNAGAACTSC | |
| SCHEMBL25528830 | 0.84 | HPGD (0.33) | — | |
| SCHEMBL25528465 | 0.84 | CACNA1H (0.33) | CACNA1H | |
| SCHEMBL25528343 | 0.83 | PARP1 (0.43) | MAP4K4CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL25528466 | 0.81 | ROCK2 (0.37) | CACNA1HGAA | |
| SCHEMBL25529759 | 0.81 | MAP4K4 (0.40) | CACNA1HMAP4K4CDK1CCNB1CCNA2 | |
| SCHEMBL25528467 | 0.78 | HTR7 (0.34) | — | |
| SCHEMBL25528475 | 0.77 | CACNA1H (0.36) | CACNA1HMAP4K4USP30 | |
| SCHEMBL25531283 | 0.77 | CACNA1H (0.36) | CACNA1HMAP4K4USP30 | |
| SCHEMBL25528470 | 0.77 | AURKA (0.37) | CACNA1HMAP4K4USP30EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093787-A1 | BENZODIAZEPINE COMPOUND AND APPLICATION THEREOF AS RHO KINASE INHIBITOR | 成都奥睿药业有限公司 | 2023-06-01 | — | — | WO | disclosed |