Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ACACB | O00763 | 5/20 | 0.51 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23986713 | 0.82 | TAAR1 (0.59) | CYP2D6SLC6A4TP53TSHRACACB | |
| SCHEMBL20862299 | 0.79 | CYP1A2 (0.70) | CYP1A2CYP2D6APEX1PMP22SLC6A4 | |
| SCHEMBL7120636 | 0.79 | SIGMAR1 (0.61) | SLC6A4TP53TSHRACACBGRIA4 | |
| SCHEMBL18211455 | 0.78 | CYP1A2 (0.68) | CYP1A2CYP2D6APEX1PMP22SLC6A4 | |
| SCHEMBL547420 | 0.77 | TSHR (0.62) | PMP22TP53TSHRACACBGRIA4 | |
| SCHEMBL13996943 | 0.76 | CYP2D6 (0.66) | CYP1A2CYP2D6APEX1PMP22SLC6A4 | |
| Iofetamine SCHEMBL11151697 | 0.76 | CYP1A2 (1.00) | CYP1A2CYP2D6APEX1PMP22SLC6A4 | |
| Iofetamine SCHEMBL3064259 | 0.76 | CYP1A2 (1.00) | CYP1A2CYP2D6APEX1PMP22SLC6A4 | |
| SCHEMBL23986761 | 0.76 | CYP1A2 (0.66) | CYP1A2CYP2D6APEX1PMP22SLC6A4 | |
| SCHEMBL13996924 | 0.76 | CYP1A2 (0.66) | CYP1A2CYP2D6APEX1PMP22SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | CYP1A2 3539/4885CYP2D6 1521/4885APEX1 263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.