Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12449602 | 0.76 | SIGMAR1 (0.51) | SIGMAR1SLC6A3MEN1KMT2ASLC6A2 | |
| SCHEMBL798027 | 0.69 | HRH3 (0.69) | SIGMAR1MEN1KMT2AHRH3LMNA | |
| SCHEMBL8352677 | 0.69 | SLC6A2 (0.51) | SIGMAR1SLC6A3HRH3SLC6A2SLC6A4 | |
| SCHEMBL5645130 | 0.66 | SLC6A2 (0.51) | SIGMAR1SLC6A3SLC6A2SLC6A4F10 | |
| SCHEMBL5827078 | 0.66 | SLC6A4 (0.59) | SLC6A3SLC6A2SLC6A4F10F2 | |
| SCHEMBL5877395 | 0.65 | SLC6A3 (0.56) | SLC6A3SLC6A2SLC6A4MAOB | |
| SCHEMBL10878264 | 0.65 | LMNA (0.41) | SLC6A3SLC6A2SLC6A4LMNA | |
| Ammonia Solution, Strong SCHEMBL5827077 | 0.64 | SLC6A4 (0.58) | SLC6A3SLC6A2SLC6A4F10F2 | |
| SCHEMBL8351046 | 0.64 | SLC6A2 (0.58) | SLC6A3MEN1KMT2AHRH3SLC6A2 | |
| SCHEMBL797735 | 0.64 | SIGMAR1 (0.60) | SIGMAR1MEN1KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | SIGMAR1 1380/4885SLC6A3 2550/4885MEN1 4216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.