Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2556380 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KDM4EL3MBTL1HTTKMT2A | |
| SCHEMBL14829657 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4EL3MBTL1HTTKMT2A | |
| SCHEMBL2474936 | 0.74 | ALDH1A1 (0.50) | ALDH1A1KDM4EL3MBTL1HTTKMT2A | |
| SCHEMBL2472101 | 0.74 | ALDH1A1 (0.50) | ALDH1A1KDM4EL3MBTL1HTTKMT2A | |
| SCHEMBL2472098 | 0.74 | ALDH1A1 (0.50) | ALDH1A1KDM4EL3MBTL1HTTKMT2A | |
| SCHEMBL2028471 | 0.73 | GABRA1 (0.51) | ALDH1A1KDM4EL3MBTL1HTTKMT2A | |
| SCHEMBL2028472 | 0.73 | GABRA1 (0.51) | ALDH1A1KDM4EL3MBTL1HTTKMT2A | |
| SCHEMBL2165060 | 0.73 | GABRA1 (0.51) | ALDH1A1KDM4EL3MBTL1HTTKMT2A | |
| Hydrochloric Acid SCHEMBL28115143 | 0.72 | PLA2G7 (0.49) | ALDH1A1KDM4EL3MBTL1HTTKMT2A | |
| SCHEMBL2447368 | 0.70 | NPFFR1 (0.43) | ALDH1A1KDM4EL3MBTL1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011124998-A1 | SUBSTITUTED 3,5- DI PHENYL - ISOXAZOLINE DERIVATIVES AS INSECTICIDES AND ACARICIDES | PFIZER INC. (US) | 2011-10-13 | — | — | WO | disclosed |