Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.54 |
| ▸ | RIPK1 | Q13546 | 6/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13093645 | 0.80 | CHRNB2 (0.51) | P2RX7RIPK1PRCPHRH3CHRNB2 | |
| SCHEMBL18950389 | 0.80 | P2RX7 (0.53) | P2RX7RIPK1PRCPCHRNB2CHRNB4 | |
| SCHEMBL20993582 | 0.80 | HRH3 (0.42) | P2RX7RIPK1HRH3CHRNB2CHRNB4 | |
| SCHEMBL1071984 | 0.79 | P2RX7 (0.50) | P2RX7RIPK1PRCPCHRNB2CHRNB4 | |
| Hydrochloric Acid SCHEMBL3670799 | 0.77 | P2RX7 (0.51) | P2RX7RIPK1PRCPCHRNA7DRD2 | |
| SCHEMBL20841306 | 0.76 | P2RX7 (0.50) | P2RX7RIPK1PRCPHRH3CHRNB2 | |
| SCHEMBL25530169 | 0.76 | HRH3 (0.43) | P2RX7RIPK1HRH3CHRNB2CHRNB4 | |
| SCHEMBL16474296 | 0.75 | RIPK1 (0.53) | P2RX7RIPK1PRCPCHRNB2CHRNB4 | |
| SCHEMBL13093649 | 0.74 | POLB (0.55) | P2RX7RIPK1HRH3NR1H2NR1H3 | |
| SCHEMBL18913873 | 0.74 | P2RX7 (0.51) | P2RX7RIPK1NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | P2RX7 2281/4885RIPK1 2036/4885PRCP 937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.