SCHEMBL25535519

SCHEMBL25535519

Cc1ccccc1-c1ccc2ccc(-c3ccc(F)cc3)cc2[n+]1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 1/20 0.39
PGR P06401 1/20 0.39
MAPT P10636 2/20 0.36
ACHE P22303 3/20 0.36
PDE2A O00408 1/20 0.35
PDE10A Q9Y233 1/20 0.35
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 1/20 0.35
ERAP1 Q9NZ08 1/20 0.34
CTSD P07339 1/20 0.34
BACE1 P56817 1/20 0.34
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP2C19 P33261 2/20 0.33
HPGD P15428 2/20 0.33
MAPK1 P28482 2/20 0.33
PDK2 Q15119 1/20 0.33
THRB P10828 1/20 0.33
S1PR1 P21453 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25535789 0.90 NR3C1 (0.41) NR3C1PGRMAPTACHEPDE2A
SCHEMBL25535780 0.85 ABL1 (0.33) PGRACHENPC1
SCHEMBL25535783 0.81 PGR (0.32) PGRALDH1A1KDM4E
SCHEMBL26612454 0.79 CYP2A6 (0.38) MAPTALDH1A1KDM4ECTSDBACE1
SCHEMBL25445417 0.77 ACHE (0.40) MAPTACHEALDH1A1HPGDMAPK1
SCHEMBL25536167 0.77 PGR (0.41) NR3C1PGRMAPTPDE2APDE10A
SCHEMBL25536079 0.77 PGR (0.41) NR3C1PGRMAPTPDE2APDE10A
SCHEMBL25535791 0.76 ABL1 (0.35) NR3C1PGRACHENPC1
SCHEMBL25452129 0.75 NR3C1 (0.41) NR3C1PGRMAPTPDE2APDE10A
SCHEMBL25452078 0.75 PTGS2 (0.42) NR3C1PGRMAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230157153-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-18 US disclosed