SCHEMBL25536167

SCHEMBL25536167

Cc1ccccc1-c1cc2cc(-c3ccc(F)cc3)ccc2c[n+]1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.41
NR3C1 P04150 1/20 0.41
CTSD P07339 1/20 0.36
BACE1 P56817 1/20 0.36
MAPT P10636 2/20 0.36
PDE2A O00408 1/20 0.34
PDE10A Q9Y233 1/20 0.34
ALDH1A1 P00352 2/20 0.34
PTGS2 P35354 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ABL1 P00519 2/20 0.33
TRPA1 O75762 1/20 0.33
THRB P10828 1/20 0.33
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP2C19 P33261 2/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
PDK2 Q15119 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25536079 0.95 PGR (0.41) PGRNR3C1CTSDBACE1MAPT
SCHEMBL25536169 0.85 ABL1 (0.35) PGRNR3C1KDM4EABL1HPGD
SCHEMBL25452079 0.80 PTGS2 (0.41) PGRNR3C1MAPTALDH1A1PTGS2
SCHEMBL25452129 0.80 NR3C1 (0.41) PGRNR3C1MAPTPDE2APDE10A
SCHEMBL25536160 0.80 ABL1 (0.38) PGRABL1
SCHEMBL26835931 0.80 CYP2A6 (0.41) CTSDBACE1MAPTALDH1A1KDM4E
SCHEMBL25452078 0.80 PTGS2 (0.42) PGRNR3C1MAPTALDH1A1PTGS2
SCHEMBL25445421 0.79 PLA2G7 (0.36) CTSDBACE1ALDH1A1TRPA1CYP2D6
SCHEMBL25535789 0.78 NR3C1 (0.41) PGRNR3C1CTSDBACE1MAPT
SCHEMBL25536162 0.77 ABL1 (0.33) PGRALDH1A1KDM4EABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230157153-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-18 US disclosed