SCHEMBL24677537

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25198909	0.76	CYP2D6 (0.40)	CYP2D6ALDH1A1NPSR1TSHRMETAP2
	SCHEMBL6483909	0.76	KMT2A (0.41)	CYP2D6ALDH1A1NPSR1L3MBTL1THRB
	SCHEMBL9359628	0.73	SMN1; SMN2 (0.32)	ALDH1A1NPSR1CHRM2CHRM4CHRM1
	SCHEMBL8330172	0.72	METAP2 (0.53)	ALDH1A1NPSR1TSHRMETAP2L3MBTL1
	SCHEMBL12691593	0.72	MMP8 (0.37)	CYP2D6ALDH1A1NPSR1TSHRMETAP2
	SCHEMBL25536207	0.72	TSHR (0.38)	CYP2D6ALDH1A1NPSR1TSHRMETAP2
	SCHEMBL25517969	0.72	ALDH1A1 (0.37)	CYP2D6ALDH1A1NPSR1TSHRMETAP2
	SCHEMBL9205786	0.72	ALDH1A1 (0.42)	ALDH1A1
	SCHEMBL19071938	0.72	ALDH1A1 (0.41)	ALDH1A1L3MBTL1THRBATMCHRM2
	SCHEMBL11021965	0.72	METAP2 (0.43)	ALDH1A1NPSR1TSHRMETAP2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.