Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25530593 | 0.77 | CYP2C19 (0.53) | PYCR1CYP1A2CYP2C19 | |
| SCHEMBL26422497 | 0.77 | LTA4H (0.33) | PYCR1CYP1A2CYP2C19LTA4H | |
| SCHEMBL14438273 | 0.71 | MAPT (0.43) | — | |
| SCHEMBL19565946 | 0.69 | S1PR1 (0.46) | PYCR1LTA4H | |
| SCHEMBL5351507 | 0.67 | IDO1 (0.52) | IDO1CYP1A2CYP2C19 | |
| SCHEMBL22763805 | 0.66 | ALDH1A1 (0.39) | CYP1A2CYP2C19 | |
| SCHEMBL13551804 | 0.66 | PYCR1 (0.47) | IDO1PYCR1CYP1A2CYP2C19LTA4H | |
| SCHEMBL16313540 | 0.63 | PYCR1 (0.47) | PYCR1 | |
| SCHEMBL13430049 | 0.62 | IDO1 (0.46) | IDO1CYP1A2CYP2C19 | |
| SCHEMBL5073332 | 0.62 | ESR1 (0.68) | IDO1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | IDO1 1403/4885PYCR1 2907/4885CYP1A2 3539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.