Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 5/20 | 0.38 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 3/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25530592 | 0.77 | CYP2C19 (0.50) | RIPK1PYCR1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL14438269 | 0.72 | RIPK1 (0.53) | RIPK1KDM4EALDH1A1 | |
| SCHEMBL901908 | 0.66 | RIPK1 (0.34) | RIPK1PYCR1SCN1ASCN5ASCN8A | |
| SCHEMBL22763805 | 0.65 | ALDH1A1 (0.39) | KDM4EALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL25488451 | 0.63 | RIPK1 (0.50) | RIPK1KDM4EALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL26076059 | 0.63 | ACHE (0.39) | — | |
| SCHEMBL20665206 | 0.62 | CYP2C19 (0.68) | RIPK1PYCR1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL25530593 | 0.62 | CYP2C19 (0.53) | PYCR1KDM4EALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL4937359 | 0.61 | NR1H2 (0.48) | KDM4EALDH1A1 | |
| SCHEMBL20238171 | 0.61 | SCN8A (0.42) | RIPK1KDM4EALDH1A1SCN1ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | RIPK1 2036/4885PYCR1 2907/4885KDM4E 3027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.