Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6589663 | 0.81 | RORC (0.54) | MAPTSMN1; SMN2HPGDNPC1CYP1A2 | |
| SCHEMBL2817587 | 0.74 | VCAM1 (0.55) | MAPTLMNAALDH1A1VCAM1KMT2A | |
| SCHEMBL57125 | 0.73 | HTT (0.68) | MAPTSMN1; SMN2HPGDNPC1CYP1A2 | |
| SCHEMBL5035528 | 0.73 | VCAM1 (0.57) | MAPTSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4656744 | 0.71 | VCAM1 (0.51) | MAPTSMN1; SMN2RORCLMNAALDH1A1 | |
| SCHEMBL11041179 | 0.70 | TDP1 (0.47) | MAPTSMN1; SMN2HPGDNPC1CYP1A2 | |
| SCHEMBL25540488 | 0.70 | MAPT (0.52) | MAPTSMN1; SMN2HPGDNPC1CYP1A2 | |
| SCHEMBL14744341 | 0.70 | MAPT (0.60) | MAPTSMN1; SMN2HPGDNPC1CYP1A2 | |
| SCHEMBL2962266 | 0.70 | SMN1; SMN2 (0.60) | MAPTSMN1; SMN2HPGDNPC1CYP1A2 | |
| SCHEMBL17125223 | 0.69 | HSD17B10 (0.60) | HPGDLMNAALDH1A1VCAM1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159549-A1 | METHOD FOR PREPARATION OF ASENAPINE | ZHEJIANG AUSUN PHARMACEUTICAL CO., LTD. (CN) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159549-A1 | METHOD FOR PREPARATION OF ASENAPINE | CYP3A5, QDPR, SPR | MAPT 727/4885SMN1; SMN2 3389/4885HPGD 1820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.