Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | DCK | P27707 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25551728 | 0.89 | LMNA (0.42) | PTGS1PTGS2LMNAMAPTFBP1 | |
| SCHEMBL25545990 | 0.88 | FBP1 (0.42) | PTGS1PTGS2FBP1DCKAAK1 | |
| SCHEMBL25556398 | 0.88 | FBP1 (0.41) | PTGS1PTGS2LMNAMAPTFBP1 | |
| SCHEMBL25545528 | 0.86 | FBP1 (0.43) | PTGS1PTGS2FBP1DCKAAK1 | |
| SCHEMBL25556360 | 0.85 | PTGS2 (0.56) | PTGS1PTGS2LMNAMAPTFBP1 | |
| SCHEMBL25550147 | 0.84 | LMNA (0.44) | PTGS1PTGS2LMNAMAPTFBP1 | |
| SCHEMBL25553879 | 0.83 | PTGS1 (0.43) | PTGS1PTGS2LMNAMAPTAAK1 | |
| SCHEMBL25550126 | 0.81 | LMNA (0.43) | PTGS1PTGS2LMNAMAPTFBP1 | |
| SCHEMBL25545551 | 0.81 | FBP1 (0.43) | PTGS1PTGS2FBP1AAK1S1PR4 | |
| SCHEMBL25556378 | 0.81 | MAPT (0.43) | PTGS1PTGS2LMNAMAPTPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | EIF4E, EIF4EBP1, EIF4A1 | PTGS1 3831/4885PTGS2 3917/4885LMNA 2647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.