Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLTP | P55058 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 2/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25556409 | 0.89 | PTGS1 (0.40) | PLTPFFAR4FBP1TLR9TLR8 | |
| SCHEMBL25545564 | 0.83 | S1PR4 (0.35) | TLR7HTR2CHTR2BHPGDPI4KB | |
| SCHEMBL25545536 | 0.83 | TNK2 (0.36) | FFAR4TLR9TLR8TLR7HTR2C | |
| SCHEMBL25545560 | 0.81 | HTT (0.40) | FBP1TLR7HTR2CHTR2B | |
| SCHEMBL25545524 | 0.81 | NR1H4 (0.36) | FFAR4TLR9TLR8TLR7HTR2C | |
| SCHEMBL25545528 | 0.81 | FBP1 (0.43) | FBP1HTR2CHTR2BHPGDPI4KB | |
| SCHEMBL25545980 | 0.81 | ALDH1A1 (0.36) | TLR9TLR8TLR7HTR2CHTR2B | |
| SCHEMBL25545547 | 0.79 | AAK1 (0.36) | FBP1TLR7HTR2CHTR2BHPGD | |
| SCHEMBL25545990 | 0.79 | FBP1 (0.42) | FBP1HTR2CHTR2BHPGDPI4KB | |
| SCHEMBL25545968 | 0.79 | CETP (0.38) | PLTPTLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-05-18 | — | — | US | disclosed |
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | EIF4E, EIF4EBP1, EIF4A1 | PLTP 3711/4885FFAR4 4777/4885FBP1 735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.