Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11476687 | 1.00 | OPRL1 (0.53) | OPRL1OPRM1OPRK1CYP2C9CYP2C19 | |
| SCHEMBL20437086 | 0.82 | TRPA1 (0.47) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL11815569 | 0.81 | OPRL1 (0.50) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL18019019 | 0.80 | CHRNA1 (0.45) | OPRL1OPRM1OPRK1CYP2C19OPRD1 | |
| SCHEMBL9542156 | 0.80 | CHRNA1 (0.45) | OPRL1OPRM1OPRK1CYP2C19OPRD1 | |
| SCHEMBL10897190 | 0.80 | OPRM1 (0.44) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL18905356 | 0.80 | DRD2 (0.35) | OPRL1OPRM1OPRK1CYP2C9CYP2C19 | |
| SCHEMBL7815717 | 0.79 | OPRL1 (0.68) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL10060840 | 0.79 | OPRL1 (0.68) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL6659407 | 0.79 | OPRL1 (0.56) | OPRL1OPRM1OPRK1OPRD1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122581-A2 | IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023081666-A1 | COMPOUNDS AS CCR2 MODULATORS | ARIA PHARMACEUTICALS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |