Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RRM1 | P23921 | 1/20 | 0.41 |
| ▸ | RRM2 | P31350 | 1/20 | 0.41 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22448499 | 0.86 | RRM1 (0.44) | RRM1RRM2RRM2BCISD1NOS3 | |
| SCHEMBL16173957 | 0.79 | RRM1 (0.41) | RRM1RRM2RRM2BCISD1NOS3 | |
| SCHEMBL13176712 | 0.79 | NOS3 (0.41) | NOS3NOS1NOS2KMT2AMEN1 | |
| SCHEMBL18024029 | 0.76 | RRM1 (0.41) | RRM1RRM2RRM2BCISD1NOS3 | |
| SCHEMBL23570007 | 0.73 | TLR8 (0.42) | RRM1RRM2RRM2BCISD1NOS3 | |
| SCHEMBL1245895 | 0.72 | MEN1 (0.50) | RRM1RRM2RRM2BCISD1KMT2A | |
| SCHEMBL31197931 | 0.72 | MEN1 (0.50) | RRM1RRM2RRM2BCISD1KMT2A | |
| SCHEMBL23612118 | 0.70 | CYP1A2 (0.39) | RRM1RRM2RRM2BCISD1NOS3 | |
| SCHEMBL23612117 | 0.70 | CYP1A2 (0.39) | RRM1RRM2RRM2BCISD1NOS3 | |
| SCHEMBL16190879 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230145249-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230145249-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | RRM1 2476/4885RRM2 656/4885RRM2B 591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.