Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 2/20 | 0.34 |
| ▸ | FNTB | P49356 | 2/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30257430 | 0.92 | GRM5 (0.38) | PHGDHSCN9ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL25251491 | 0.92 | GRM5 (0.38) | PHGDHSCN9ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL25554410 | 0.90 | PHGDH (0.41) | PHGDHSCN9ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL25554317 | 0.87 | SCN9A (0.41) | PHGDHSCN9ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL30353060 | 0.87 | SCN9A (0.41) | PHGDHSCN9ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL25554325 | 0.86 | SCN9A (0.38) | PHGDHSCN9ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL25554810 | 0.85 | CRHR1 (0.33) | SCN9ACYP19A1CYP11B1CYP11B2CTSA | |
| SCHEMBL25554247 | 0.85 | CYP11B1 (0.41) | PHGDHSCN9ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL30257529 | 0.85 | NR3C1 (0.33) | CYP19A1CYP11B1CYP11B2GRM5ALOX5AP | |
| SCHEMBL25267103 | 0.85 | NR3C1 (0.33) | CYP19A1CYP11B1CYP11B2GRM5ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167073-A1 | ARYL OR HETEROARYL DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2023-06-01 | — | — | US | disclosed |
| US-20230167073-A1 | ARYL OR HETEROARYL DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167073-A1 | ARYL OR HETEROARYL DERIVATIVE | ARRB1, NR3C2, TRPC6 | PHGDH 4304/4885SCN9A 760/4885CYP19A1 3966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.