Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25565777 | 0.88 | ALDH1A1 (0.50) | ALDH1A1ALOX5GLA | |
| SCHEMBL23341749 | 0.81 | NPC1 (0.45) | ALDH1A1ALOX5GLAPTGS2NPC1 | |
| SCHEMBL16221704 | 0.80 | ALOX5 (0.41) | ALDH1A1ALOX5NPC1HSP90AB1CYP1A2 | |
| SCHEMBL22803422 | 0.79 | DGAT1 (0.41) | HSP90AB1 | |
| SCHEMBL20362413 | 0.78 | CYP1A2 (0.40) | CYP1A2 | |
| SCHEMBL20953397 | 0.77 | CYP19A1 (0.36) | HSP90AB1 | |
| SCHEMBL20711246 | 0.76 | KDM4E (0.35) | ALDH1A1GLACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20694373 | 0.76 | HSP90AB1 (0.41) | ALOX5HSP90AB1 | |
| SCHEMBL15431475 | 0.76 | ALOX5 (0.36) | ALDH1A1ALOX5GLANPC1HSP90AB1 | |
| SCHEMBL20694535 | 0.75 | DGAT1 (0.40) | HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230149562-A1 | CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY | TIBA BIOTECH LLC (US) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230149562-A1 | CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY | POLN, TLR9, TSG101 | ALDH1A1 3979/4885ALOX5 4067/4885GLA 3196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.