Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | CSF1R | P07333 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25567411 | 0.82 | ALDH1A1 (0.49) | RAB9ANPC1CSF1RMAPK14BRAF | |
| SCHEMBL25564759 | 0.81 | MAPK14 (0.58) | RAB9ANPC1CSF1RMAPK14KMT2A | |
| SCHEMBL25565785 | 0.77 | RAF1 (0.49) | RAB9ANPC1CSF1RMAPK14MAPT | |
| SCHEMBL1257102 | 0.75 | RAB9A (0.72) | RAB9ANPC1CSF1RMAPK14MAPT | |
| SCHEMBL155351 | 0.75 | HDAC3 (0.42) | — | |
| SCHEMBL25567722 | 0.74 | MAPK14 (0.46) | RAB9ANPC1CSF1RMAPK14KMT2A | |
| SCHEMBL152807 | 0.74 | HDAC3 (0.45) | POLB | |
| SCHEMBL25565793 | 0.74 | HDAC3 (0.38) | EPHX2 | |
| SCHEMBL13234413 | 0.74 | RAB9A (1.00) | RAB9ANPC1MAPK14MAPTHTT | |
| SCHEMBL25567414 | 0.74 | HDAC3 (0.41) | KMT2AEPHX2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078207-A1 | 6-POSITION-SUBSTITUTED INDOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 南京中医药大学 | 2023-05-11 | — | — | WO | disclosed |