Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25567804 | 0.83 | NR4A1 (0.41) | HPGDCES2CES1ALDH1A1CYP11B1 | |
| SCHEMBL25568752 | 0.82 | TSHR (0.50) | HPGDTSHRALDH1A1HTT | |
| SCHEMBL25567195 | 0.82 | HSD11B1 (0.40) | POLBHPGDTSHRALDH1A1RAB9A | |
| SCHEMBL25567427 | 0.81 | POLB (0.46) | POLBHPGDTSHRALDH1A1CYP2C19 | |
| SCHEMBL1647150 | 0.79 | MEN1 (0.52) | HPGDTSHRTP53ALDH1A1 | |
| SCHEMBL25568956 | 0.79 | ERN1 (0.38) | HPGDTP53ALDH1A1HTTRAB9A | |
| SCHEMBL24250390 | 0.78 | MEN1 (0.44) | POLBTSHRTP53ALDH1A1 | |
| SCHEMBL25567408 | 0.77 | LMNA (0.44) | CYP3A4 | |
| SCHEMBL18616928 | 0.76 | MEN1 (0.43) | POLBHPGDTSHRTP53ALDH1A1 | |
| SCHEMBL19020742 | 0.75 | MEN1 (0.39) | POLBHPGDTSHRTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097386-A1 | SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS | EUROFARMA LABORATÓRIOS S.A (BR) | 2023-06-08 | — | — | WO | disclosed |