Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25567195 | 0.88 | HSD11B1 (0.40) | HPGDMAPK1LMNANPC1RECQL | |
| SCHEMBL25567428 | 0.83 | POLB (0.53) | HPGDCYP2C19CYP2C9CYP3A4CES2 | |
| SCHEMBL25568956 | 0.81 | ERN1 (0.38) | MAPTHPGDNPC1ERN1ALDH1A1 | |
| SCHEMBL25567789 | 0.81 | ALDH1A1 (0.44) | MAPTLMNANPC1CYP2D6CYP2C9 | |
| SCHEMBL25568752 | 0.78 | TSHR (0.50) | HPGDMAPK1LMNANPC1ALDH1A1 | |
| SCHEMBL11608426 | 0.78 | NR4A1 (0.61) | NR4A1MAPTCYP1A2CYP2C19MAPK1 | |
| SCHEMBL1647150 | 0.76 | MEN1 (0.52) | MAPTHPGDLMNAERN1ALDH1A1 | |
| SCHEMBL24250390 | 0.74 | MEN1 (0.44) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL25567408 | 0.73 | LMNA (0.44) | LMNACYP2D6CYP3A4ERN1SMN1; SMN2 | |
| SCHEMBL6520356 | 0.73 | NR4A1 (0.42) | NR4A1MAPTCYP1A2HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097386-A1 | SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS | EUROFARMA LABORATÓRIOS S.A (BR) | 2023-06-08 | — | — | WO | disclosed |