Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11216342 | 0.86 | KMT2A (0.59) | TSHRALDH1A1KMT2AMAPK1MEN1 | |
| SCHEMBL25567195 | 0.83 | HSD11B1 (0.40) | TSHRALDH1A1KMT2AMAPK1LMNA | |
| SCHEMBL25567428 | 0.82 | POLB (0.53) | TSHRALDH1A1HPGDHTT | |
| SCHEMBL1647150 | 0.80 | MEN1 (0.52) | TSHRALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL24250390 | 0.79 | MEN1 (0.44) | TSHRALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL14646679 | 0.79 | ALDH1A1 (0.57) | TSHRALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL25567408 | 0.78 | LMNA (0.44) | LMNASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25567804 | 0.78 | NR4A1 (0.41) | ALDH1A1KMT2AMAPK1LMNAMEN1 | |
| SCHEMBL18616928 | 0.77 | MEN1 (0.43) | TSHRALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL12205237 | 0.75 | KMT2A (0.57) | TSHRKMT2AMAPK1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097386-A1 | SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS | EUROFARMA LABORATÓRIOS S.A (BR) | 2023-06-08 | — | — | WO | disclosed |