Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 9/20 | 0.65 |
| ▸ | HSD17B2 | P37059 | 8/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | NT5E | P21589 | 2/20 | 0.57 |
| ▸ | ESR1 | P03372 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 2/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7898375 | 0.81 | HSD17B1 (1.00) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL571400 | 0.81 | — | — | |
| SCHEMBL27653097 | 0.79 | ESR1 (0.55) | HSD17B1HSD17B2CYP3A4NT5EESR1 | |
| SCHEMBL28219578 | 0.79 | LPL (0.44) | HSD17B1HSD17B2NT5EERN1 | |
| SCHEMBL8050006 | 0.78 | HSD17B1 (0.94) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL3014918 | 0.77 | HSD17B1 (1.00) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL1794873 | 0.77 | CNR1 (0.41) | HSD17B1HSD17B2NT5EFYNERN1 | |
| SCHEMBL29404406 | 0.77 | HSD17B1 (1.00) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL29832647 | 0.77 | HSD17B1 (0.90) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL70625 | 0.77 | HSD17B1 (1.00) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167447-A1 | Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof | GENETIC INTELLIGENCE INC (US) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167447-A1 | Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof | FNIP1, FN1, TNNC1 | HSD17B1 4401/4885HSD17B2 4421/4885CYP3A4 4799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.