SCHEMBL25567762

SCHEMBL25567762

N#Cc1ccc2c(c1)C1c3ccccc3C2c2cc(-c3cccc4c5ccccc5c5ccccc5c34)c(C#N)cc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
STS P08842 1/20 0.33
MYB P10242 1/20 0.32
ADRA2C P18825 1/20 0.32
CHRNA1 P02708 1/20 0.32
CHRNG P07510 1/20 0.32
CHRNB1 P11230 1/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA4 P43681 1/20 0.32
CHRND Q07001 1/20 0.32
MGLL Q99685 1/20 0.32
CCNB2 O95067 1/20 0.31
CDK1 P06493 1/20 0.31
CCNB1 P14635 1/20 0.31
CCNA2 P20248 1/20 0.31
CDK2 P24941 1/20 0.31
GSK3B P49841 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25567565 0.93 ALDH1A1 (0.34) CA1CA2GABRA1GABRG2GABRB3
SCHEMBL25568068 0.86 CA1 (0.43) CA1CA2MYBSLC6A4ALDH1A1
SCHEMBL25567624 0.83 ADRA2C (0.38) STSADRA2CGABRA1GABRG2GABRB3
SCHEMBL25567934 0.80 PLG (0.35) CA1CA2STSADRA2CGABRA1
SCHEMBL25567820 0.78 STS (0.39) STSADRA2CGSK3BGABRA1GABRG2
SCHEMBL25567919 0.78 SLC9A1 (0.36) GABRA1GABRG2GABRB3GABRA2ALDH1A1
SCHEMBL25566853 0.78 CHRNA1 (0.46) CA1CA2ADRA2CCHRNA1CHRNG
SCHEMBL25567916 0.76 POLB (0.38) CA1CA2ALDH1A1HPGDTSHR
SCHEMBL25567824 0.75 STS (0.40) CA1CA2STSGABRA1GABRG2
SCHEMBL25566977 0.75 CHRNA1 (0.36) CA1CA2CHRNA1CHRNGCHRNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023094412-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-06-01 WO disclosed