SCHEMBL25567807

SCHEMBL25567807

COC1Oc2ccccc2-c2ccccc2C1=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NT5E P21589 3/20 0.43
PGR P06401 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
POLB P06746 1/20 0.41
NPC1 O15118 2/20 0.40
MAPT P10636 2/20 0.40
RAB9A P51151 2/20 0.40
MAOB P27338 2/20 0.40
HPGD P15428 2/20 0.39
TP53 P04637 1/20 0.39
MAOA P21397 1/20 0.39
PTGS2 P35354 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KDM4E B2RXH2 5/20 0.38
ALDH1A1 P00352 3/20 0.38
HSD17B10 Q99714 3/20 0.38
CYP19A1 P11511 3/20 0.38
ADORA3 P0DMS8 1/20 0.38
AR P10275 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4334851 0.93 NT5E (0.45) NT5EPGRMEN1KMT2APOLB
SCHEMBL7534480 0.75 MEN1 (0.43) NT5EMEN1KMT2ANPC1MAPT
SCHEMBL67633 0.72 POLB (0.46) MEN1KMT2APOLBNPC1MAPT
SCHEMBL10708762 0.72 NT5E (0.39) NT5ENPC1MAPTRAB9AMAOB
SCHEMBL5457239 0.71 RET (0.40) MEN1KMT2APOLBNPC1MAPT
SCHEMBL3410904 0.70 GRM1 (0.39) NT5EPGRMEN1KMT2ANPC1
SCHEMBL3410906 0.70 GRM1 (0.39) NT5EPGRMEN1KMT2ANPC1
SCHEMBL7539076 0.68 ALDH1A1 (0.49) MEN1KMT2APOLBMAPTHPGD
SCHEMBL2631833 0.68 ALDH1A1 (0.48) POLBMAPTRAB9AHPGDTP53
SCHEMBL7114128 0.68 PGR (0.37) NT5EPGRPOLBNPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167447-A1 Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof GENETIC INTELLIGENCE INC (US) 2023-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167447-A1 Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof FNIP1, FN1, TNNC1 NT5E 2377/4885PGR 2983/4885MEN1 3817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.