Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 17/20 | 0.73 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.61 |
| ▸ | MAOA | P21397 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6345667 | 0.88 | KMT2A (0.61) | MAOBADORA2BRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL12325917 | 0.88 | MAOB (0.65) | MAOBADORA2BMAOAL3MBTL1 | |
| SCHEMBL1253672 | 0.84 | MAOB (1.00) | MAOBADORA2BMAOA | |
| SCHEMBL30059662 | 0.84 | MAOB (1.00) | MAOBADORA2BMAOA | |
| SCHEMBL13856767 | 0.84 | MAOB (0.67) | MAOBMAOARAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL11495712 | 0.81 | MAOB (0.56) | MAOBADORA2BMAOA | |
| SCHEMBL12326547 | 0.80 | ALDH1A1 (0.69) | MAOBADORA2BMAOARAB9AKMT2A | |
| SCHEMBL9029206 | 0.79 | MAOB (0.72) | MAOBADORA2BMAOA | |
| SCHEMBL4974849 | 0.79 | MAOB (0.72) | MAOBADORA2BMAOARAB9ASMN1; SMN2 | |
| SCHEMBL4519275 | 0.79 | MAOB (0.72) | MAOBADORA2BMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240391928-A1 | COMPOSITIONS FOR THE TREATMENT OF FOOD AND CHEMICAL ADDICTION AND METHODS OF MAKING AND USING SAME | UNIV DUKE (US) | 2024-11-28 | — | — | US | disclosed |
| EP-4404926-A1 | COMPOSITIONS FOR THE TREATMENT OF FOOD AND CHEMICAL ADDICTION AND METHODS OF MAKING AND USING SAME | Duke University (US) | 2024-07-31 | — | — | EP | disclosed |
| US-20230167447-A1 | Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof | GENETIC INTELLIGENCE INC (US) | 2023-06-01 | — | — | US | disclosed |
| WO-2023048762-A1 | COMPOSITIONS FOR THE TREATMENT OF FOOD AND CHEMICAL ADDICTION AND METHODS OF MAKING AND USING SAME | DUKE UNIVERSITY (US) | 2023-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167447-A1 | Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof | FNIP1, FN1, TNNC1 | MAOB 1788/4885ADORA2B 4508/4885MAOA 1681/4885 |
| US-20240391928-A1 | COMPOSITIONS FOR THE TREATMENT OF FOOD AND CHEMICAL ADDICTION AND METHODS OF MAKING AND USING SAME | PNMT, DBH, COMT | MAOB 33/4885ADORA2B 527/4885MAOA 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.