SCHEMBL25568680

SCHEMBL25568680

N#Cc1ccc(-c2cc3c(cc2C#N)C2c4cc(C#N)c(-c5ccc(C#N)cc5)cc4C3c3cc(-c4ccc(C#N)cc4)c(C#N)cc32)cc1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
STS P08842 1/20 0.44
CYP11B2 P19099 11/20 0.42
CYP11B1 P15538 6/20 0.42
MMP3 P08254 1/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
KDM1A O60341 1/20 0.38
MAOA P21397 1/20 0.38
KIF11 P52732 2/20 0.36
LAP3 P28838 1/20 0.36
PTGS1 P23219 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25567824 0.92 STS (0.40) STSCYP11B2CYP11B1MMP3CA12
SCHEMBL25568998 0.84 AR (0.42) CYP11B2CYP11B1KDM1AMAOA
SCHEMBL25567820 0.83 STS (0.39) STSCYP11B2MAOA
SCHEMBL25568572 0.83 ALDH1A1 (0.42) MAOA
SCHEMBL25568831 0.81 KIF11 (0.50) STSCYP11B2CYP11B1KDM1AMAOA
SCHEMBL25567624 0.76 ADRA2C (0.38) STSCYP11B2MAOA
SCHEMBL19917526 0.76 KIF11 (0.46) STSCYP11B2CYP11B1MMP3KIF11
SCHEMBL25568679 0.75 PGR (0.31)
SCHEMBL21189129 0.70 MMP3 (0.39) STSCYP11B2CYP11B1MMP3KDM1A
SCHEMBL23624582 0.70 ALDH1A1 (0.54) STSCYP11B2MMP3KDM1AKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023094412-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-06-01 WO disclosed