Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.30 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19782068 | 0.84 | POLB (0.38) | POLBSMN1; SMN2CXCR4RAD52SIGMAR1 | |
| SCHEMBL24480972 | 0.82 | OPRM1 (0.31) | GNAO1 | |
| SCHEMBL22565133 | 0.78 | — | — | |
| SCHEMBL22566297 | 0.78 | — | — | |
| SCHEMBL25565790 | 0.78 | ACHE (0.53) | POLBSIGMAR1 | |
| SCHEMBL24480857 | 0.78 | ACHE (0.40) | POLBSMN1; SMN2CXCR4RAD52SIGMAR1 | |
| SCHEMBL25074009 | 0.77 | NCF1 (0.39) | POLBSMN1; SMN2CXCR4RAD52SIGMAR1 | |
| SCHEMBL18883293 | 0.77 | NCF1 (0.39) | POLBSMN1; SMN2CXCR4RAD52SIGMAR1 | |
| SCHEMBL945557 | 0.75 | NCF1 (0.45) | POLBSMN1; SMN2CXCR4RAD52SIGMAR1 | |
| SCHEMBL23874494 | 0.74 | ACHE (0.40) | POLBSMN1; SMN2CXCR4RAD52SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083194-A1 | WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF | 杭州格博生物医药有限公司 | 2023-05-19 | — | — | WO | disclosed |