Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PFKFB3 | Q16875 | 3/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24932464 | 0.93 | ALDH1A1 (0.35) | ALDH1A1HSD17B10TGFBR1NPC1RAB9A | |
| SCHEMBL15912333 | 0.86 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TGFBR1NPC1RAB9A | |
| SCHEMBL17132538 | 0.80 | TGFBR1 (0.35) | ALDH1A1HSD17B10TGFBR1NPC1RAB9A | |
| SCHEMBL24253405 | 0.80 | LMNA (0.38) | ALDH1A1HSD17B10TGFBR1NPC1RAB9A | |
| SCHEMBL30093444 | 0.80 | GAA (0.45) | ALDH1A1HSD17B10TGFBR1NPC1RAB9A | |
| SCHEMBL4048510 | 0.80 | GAA (0.45) | ALDH1A1HSD17B10TGFBR1NPC1RAB9A | |
| SCHEMBL24611377 | 0.79 | ALDH1A1 (0.33) | ALDH1A1HSD17B10TGFBR1NPC1RAB9A | |
| SCHEMBL24447316 | 0.77 | TAS1R3 (0.38) | ALDH1A1HSD17B10TGFBR1NPC1RAB9A | |
| SCHEMBL24253408 | 0.76 | LMNA (0.38) | ALDH1A1HSD17B10TGFBR1NPC1RAB9A | |
| SCHEMBL24984324 | 0.76 | TGFBR1 (0.35) | ALDH1A1HSD17B10TGFBR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086400-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |